Entrepreneurship and creativity are often used in the same place and statistics increasingly show that athletes have the most motivation to start a self-employment business. Global changes have created economic opportunities for athletes who are eager to own and operate businesses. Sport entrepreneurship appears to be a most rapidly growing business sector in the world and is an important factor in the national economic growth. In this study, the relationship between creativity and entrepreneurship in athletes and non-athletes was investigated. The statistical population consisted of all Yazd university students. 346 male students and 354 female students were selected as the sample by Morgan table. The results showed no significant relationship between creativity and entrepreneurship in athletes and non-athletes but there was a relationship between creativity and entrepreneurship in male athletes and male non-athletes.